According to the need of photogrammetry and the characteristics of multi-rotor UAV(unmanned aerial vehicle),a scheme of oblique image acquisition using single-lens camera is proposed through analyzing the principle of conventional multi-lens camera in terms of hardware selection,process optimization and software research, and its feasibility is verified through experiment. Furthermore, the key processes of the multi-rotor UAV using single-lens camera are presented, including route planning method and aerial quality control standard. Besides,a mobile ground station App oriented to the demand of oblique image acquisition is designed.Test results show that under given operation standards,the multi-rotor UAV with single-lens camera could well implement 3D ground modeling.